Do you think you have De Quervain’s Tenosynovitis? I seem to have had a few patients come in complainig of a wrist pain at the base of their thumbs, especially with grasping and holding items in their hand. The condition causing the wrist pain for these patients is likely to be de Quervain’s Tenosynovitis. So what are the symptoms, causes and treatment options if you think you have de Quervain’s Tenosynovitis. Take a look at the de Quervain’s disease information below on what I found out today about this inflammatory condition of the wrist.